J. Cogn. Neurosci.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Mayer, A. R.
Right arrow Articles by Rao, S. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mayer, A. R.
Right arrow Articles by Rao, S. M.
(Journal of Cognitive Neuroscience. 2004;16:1262-1271.)
© 2004 The MIT Press

An Event-related fMRI Study of Exogenous Orienting: Supporting Evidence for the Cortical Basis of Inhibition of Return?

Andrew R. Mayer1,2, Michael Seidenberg4, Jill M. Dorflinger3,4 and Stephen M. Rao3,4

1 The MIND Institute, 2 University of New Mexico School of Medicine, 3 Medical College of Wisconsin, 4 The Finch University of Health Sciences/The Chicago Medical School

This event-related fMRI experiment examined the neural substrates of exogenous visuospatial attention. Exogenous attention produces a biphasic response pattern denoted by facilitation at short cue–target intervals and inhibition of return (IOR) at longer intervals. Whereas the volitional orienting of attention has been well described in the literature, the neural systems that support exogenous facilitation and IOR in humans are relatively unknown. In direct comparisons to valid facilitation trials, valid IOR trials produced unique foci of activation in the right posterior parietal, superior temporal, middle temporal, middle occipital, anterior cingulate, and dorsal medial thalamic areas. Valid IOR trials also resulted in activation of motor exploratory and frontal areas previously associated with inhibition and oculomotor control. In contrast, invalid IOR compared to facilitation trials only activated anterior cortical structures. These results provide support for both attentional and oculomotor theories of IOR and suggest that IOR may be mediated by two networks. One network may mediate the inhibitory bias following an exogenous cue, whereas a separate network may be activated when a response must be made to stimuli that appear in inhibited locations of space.


Key Words: Exogenous • visual–spatial • attention • inhibition of return • fMRI • event-related




This article has been cited by other articles:


Home page
 J. Cogn. Neurosci.Home page
B. Pastotter, S. Hanslmayr, and K.-H. Bauml
Inhibition of return arises from inhibition of response processes: an analysis of oscillatory Beta activity.
J. Cogn. Neurosci., January 1, 2008; 20(1): 65 - 75.
[Abstract] [Full Text] [PDF]

Home page
 J. Cogn. Neurosci.Home page
A. R. Mayer, D. L. Harrington, J. Stephen, J. C. Adair, and R. R. Lee
An Event-related fMRI Study of Exogenous Facilitation and Inhibition of Return in the Auditory Modality.
J. Cogn. Neurosci., March 1, 2007; 19(3): 455 - 467.
[Abstract] [Full Text] [PDF]

Home page
 J. Cogn. Neurosci.Home page
Q. Chen, P. Wei, and X. Zhou
Distinct neural correlates for resolving stroop conflict at inhibited and noninhibited locations in inhibition of return.
J. Cogn. Neurosci., November 1, 2006; 18(11): 1937 - 1946.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
J. M. Kincade, R. A. Abrams, S. V. Astafiev, G. L. Shulman, and M. Corbetta
An Event-Related Functional Magnetic Resonance Imaging Study of Voluntary and Stimulus-Driven Orienting of Attention
J. Neurosci., May 4, 2005; 25(18): 4593 - 4604.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
NEURAL COMPUTATION J COGNITIVE NEUROSCIENCE MIT PRESS JOURNALS
Copyright © 2004 by The MIT Press.