| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Article |
a Georgetown University Medical Center
b University of Maryland, School of Medicine
Georgetown Institute for Cognitive and Computational Sciences, The Research Building EP04, 3900 Reservior Road NW, Washington, DC 20007-2197, USA. Tel.: +1-410-402-6028; e-mail: malle{at}giccs.georgetown.edu
Also corresponding author. Tel.: +1-202-784-4134; fax: +1-202-687-6914; e-mail: rbf{at}giccs.georgetown.edu
Brain activation studies of orthographic stimuli typically start with the premise that different types of orthographic strings (e.g., words, pseudowords) differ from each other in discrete ways, which should be reflected in separate and distinct areas of brain activation. The present study starts from a different premise: Words, pseudowords, letterstrings, and false fonts vary systematically across a continuous dimension of familiarity to English readers. Using a one-back matching task to force encoding of the stimuli, the four types of stimuli were visually presented to healthy adult subjects while fMRI activations were obtained. Data analysis focused on parametric comparisons of fMRI activation sites. We did not find any region that was exclusively activated for real words. Rather, differences among these string types were mainly expressedas graded changes in the balance of activations among the regions. Our results suggest that there is a widespread network of brain regions that form a common network for the processing of all orthographic string types.
This article has been cited by other articles:
|
|
 |
|
  U. Maurer, J. D. Zevin, and B. D. McCandliss Left-lateralized N170 Effects of Visual Expertise in Reading: Evidence from Japanese Syllabic and Logographic Scripts J. Cogn. Neurosci., October 1, 2008; 20(10): 1878 - 1891. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. S. Ghosh, J. A. Tourville, and F. H. Guenther A Neuroimaging Study of Premotor Lateralization and Cerebellar Involvement in the Production of Phonemes and Syllables J Speech Lang Hear Res, October 1, 2008; 51(5): 1183 - 1202. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Xue and R. A. Poldrack The neural substrates of visual perceptual learning of words: implications for the visual word form area hypothesis. J. Cogn. Neurosci., October 1, 2007; 19(10): 1643 - 1655. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. I. Baker, J. Liu, L. L. Wald, K. K. Kwong, T. Benner, and N. Kanwisher Visual word processing and experiential origins of functional selectivity in human extrastriate cortex PNAS, May 22, 2007; 104(21): 9087 - 9092. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Xue, C. Chen, Z. Jin, and Q. Dong Cerebral asymmetry in the fusiform areas predicted the efficiency of learning a new writing system. J. Cogn. Neurosci., June 1, 2006; 18(6): 923 - 931. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Mechelli, J. T. Crinion, S. Long, K. J. Friston, M. A. Lambon Ralph, K. Patterson, J. L. McClelland, and C. J. Price Dissociating Reading Processes on the Basis of Neuronal Interactions J. Cogn. Neurosci., November 1, 2005; 17(11): 1753 - 1765. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
U. Maurer, S. Brem, K. Bucher, and D. Brandeis Emerging Neurophysiological Specialization for Letter Strings J. Cogn. Neurosci., October 1, 2005; 17(10): 1532. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 I. Kahn, A. Pascual-Leone, H. Theoret, F. Fregni, D. Clark, and A. D. Wagner Transient Disruption of Ventrolateral Prefrontal Cortex During Verbal Encoding Affects Subsequent Memory Performance J Neurophysiol, July 1, 2005; 94(1): 688 - 698. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Coch, G. Grossi, W. Skendzel, and H. Neville ERP Nonword Rhyming Effects in Children and Adults J. Cogn. Neurosci., January 1, 2005; 17(1): 168 - 182. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Z. Rapcsak and P. M. Beeson The role of left posterior inferior temporal cortex in spelling Neurology, June 22, 2004; 62(12): 2221 - 2229. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Ischebeck, P. Indefrey, N. Usui, I. Nose, F. Hellwig, and M. Taira Reading in a Regular Orthography: An fMRI Study Investigating the Role of Visual Familiarity J. Cogn. Neurosci., June 1, 2004; 16(5): 727 - 741. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Proverbio, L. Vecchi, and A. Zani From Orthography to Phonetics: ERP Measures of Grapheme-to-Phoneme Conversion Mechanisms in Reading J. Cogn. Neurosci., February 1, 2004; 16(2): 301 - 317. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Cohen, O. Martinaud, C. Lemer, S. Lehericy, Y. Samson, M. Obadia, A. Slachevsky, and S. Dehaene Visual Word Recognition in the Left and Right Hemispheres: Anatomical and Functional Correlates of Peripheral Alexias Cereb Cortex, December 1, 2003; 13(12): 1313 - 1333. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Burton, J. B. Diamond, and K. B. McDermott Dissociating Cortical Regions Activated by Semantic and Phonological Tasks: A fMRI Study in Blind and Sighted People J Neurophysiol, September 1, 2003; 90(3): 1965 - 1982. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Burton Visual Cortex Activity in Early and Late Blind People J. Neurosci., May 15, 2003; 23(10): 4005 - 4011. [Full Text] [PDF]
|
|
|
|
|
|
A. Mechelli, M. L. Gorno-Tempini, and C. J. Price Neuroimaging Studies of Word and Pseudoword Reading: Consistencies, Inconsistencies, and Limitations J. Cogn. Neurosci., February 1, 2003; 15(2): 260 - 271. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W.D. Gaillard, L.M. Balsamo, Z. Ibrahim, B.C. Sachs, and B. Xu fMRI identifies regional specialization of neural networks for reading in young children Neurology, January 14, 2003; 60(1): 94 - 100. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Burton, A. Z. Snyder, J. B. Diamond, and M. E. Raichle Adaptive Changes in Early and Late Blind: A fMRI Study of Verb Generation to Heard Nouns J Neurophysiol, December 1, 2002; 88(6): 3359 - 3371. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Chen, S. Fu, S. D. Iversen, S. M. Smith, and P. M. Matthews Testing for Dual Brain Processing Routes in Reading: A Direct Contrast of Chinese Character and Pinyin Reading Using fMRI J. Cogn. Neurosci., October 1, 2002; 14(7): 1088 - 1098. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Cohen, S. Lehericy, F. Chochon, C. Lemer, S. Rivaud, and S. Dehaene Language-specific tuning of visual cortex? Functional properties of the Visual Word Form Area Brain, May 1, 2002; 125(5): 1054 - 1069. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. A. Polk, M. Stallcup, G. K. Aguirre, D. C. Alsop, M. D'Esposito, J. A. Detre, and M. J. Farah Neural Specialization for Letter Recognition J. Cogn. Neurosci., February 1, 2002; 14(2): 145 - 159. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. J. Fiebach, A. D. Friederici, K. Muller, and D. Y. von Cramon fMRI Evidence for Dual Routes to the Mental Lexicon in Visual Word Recognition J. Cogn. Neurosci., January 1, 2002; 14(1): 11 - 23. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Grossman and T. Nakada A letter is a letter is a letter: Pure alexia for kana Neurology, March 27, 2001; 56(6): 699 - 701. [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| NEURAL COMPUTATION | J COGNITIVE NEUROSCIENCE | MIT PRESS JOURNALS |
